Exhibit 2.2. Most Frequent Diagnoses by Age Number of Discharges and Percent Distribution of the Most Frequent Principal Diagnoses by Age, 1997, 2004, 2005
Principal Diagnosis CCS Condition Category and Name Number of Discharges in Thousands Standard Errors in Thousands Percent of Total Discharges Percent of Age-specific Total Discharges
1997 2004 2005 1997 2004 2005 1997 2004 2005 1997 2004 2005
All ages* 34,678.7 38,661.8 39,163.8 653.509 707.463 765.017 100.0 100.0 100.0
< 1 year 4,426.0 4,897.6 4,977.5 142.621 156.010 166.359 12.8 12.7 12.7 100.0 100.0 100.0
218 Liveborn (newborn infant) 3,776.4 4,244.1 4,223.2 130.206 144.782 157.008 10.9 11.0 10.8 85.3 86.7 84.8
125 Acute bronchitis 108.2 111.5 107.3 6.338 8.460 8.954 0.3 0.3 0.3 2.4 2.3 2.2
222 Hemolytic jaundice and perinatal jaundice (infant jaundice following birth) 33.1 46.7 56.5 1.622 2.597 3.218 0.1 0.1 0.1 0.7 1.0 1.1
122 Pneumonia (except that caused by tuberculosis or sexually transmitted disease) 55.5 38.8 43.4 3.334 2.144 3.198 0.2 0.1 0.1 1.3 0.8 0.9
219 Short gestation, low birth weight, and fetal growth retardation (premature birth and low birth weight) 22.2 25.3 31.2 1.887 3.323 3.998 0.1 0.1 0.1 0.5 0.5 0.6
1-17 years 1,820.7 1,784.5 2,059.1 93.205 115.169 173.661 5.3 4.6 5.3 100.0 100.0 100.0
122 Pneumonia (except that caused by tuberculosis or sexually transmitted disease) 135.3 107.6 142.5 6.324 5.647 10.109 0.4 0.3 0.4 7.4 6.0 6.9
128 Asthma 158.6 132.9 139.4 10.744 10.497 13.582 0.5 0.3 0.4 8.7 7.4 6.8
55 Fluid and electrolyte disorders (primarily dehydration or fluid overload) 64.0 78.5 98.2 4.134 4.781 6.419 0.2 0.2 0.3 3.5 4.4 4.8
142 Appendicitis and other appendiceal conditions 65.2 82.4 89.5 2.500 4.960 6.770 0.2 0.2 0.2 3.6 4.6 4.3
657 Mood disorders (depression and bipolar disorder) 64.1 83.6 73.3 6.702 11.926 10.565 0.2 0.2 0.2 3.5 4.7 3.6
18-44 years 9,443.7 10,323.4 10,040.8 242.754 233.792 255.013 27.2 26.7 25.6 100.0 100.0 100.0
193 Trauma to external female genitals (vulva) and area between anus and vagina (perineum) 675.5 754.3 753.0 28.176 32.592 34.989 1.9 2.0 1.9 7.2 7.3 7.5
189 Previous C-section 269.7 453.0 477.9 10.195 17.126 19.509 0.8 1.2 1.2 2.9 4.4 4.8
657 Mood disorders (depression and bipolar disorder) 334.6 416.4 363.7 18.717 24.081 23.010 1.0 1.1 0.9 3.5 4.0 3.6
196 Normal pregnancy and/or delivery 511.4 323.3 312.1 18.671 12.840 12.933 1.5 0.8 0.8 5.4 3.1 3.1
190 Fetal distress and abnormal forces of labor 398.9 237.9 224.4 19.417 11.321 9.394 1.2 0.6 0.6 4.2 2.3 2.2
45-64 years 6,496.2 8,546.4 8,660.0 146.494 177.790 201.052 18.7 22.1 22.1 100.0 100.0 100.0
101 Coronary atherosclerosis (coronary artery disease) 526.1 492.1 460.8 21.811 20.132 21.111 1.5 1.3 1.2 8.1 5.8 5.3
102 Non-specific chest pain 242.1 395.9 387.9 7.545 11.575 15.615 0.7 1.0 1.0 3.7 4.6 4.5
203 Osteoarthritis (degenerative joint disease) 105.3 234.7 271.6 3.971 10.436 11.403 0.3 0.6 0.7 1.6 2.7 3.1
122 Pneumonia (except that caused by tuberculosis or sexually transmitted disease) 199.0 246.0 271.0 4.170 5.000 6.910 0.6 0.6 0.7 3.1 2.9 3.1
205 Spondylosis, intervertebral disc disorders, other back problems (disorders of intervertebral discs and bones in spinal column) 190.4 249.5 265.6 7.731 10.183 12.871 0.5 0.6 0.7 2.9 2.9 3.1
65+ years 12,482.4 13,059.2 13,374.5 249.169 272.444 314.974 36.0 33.8 34.2 100.0 100.0 100.0
108 Congestive heart failure, nonhypertensive 783.0 820.5 815.1 16.786 18.959 16.786 2.3 2.1 2.1 6.3 6.3 6.1
122 Pneumonia (except that caused by tuberculosis or sexually transmitted disease) 710.6 712.7 781.1 13.469 13.824 13.469 2.0 1.8 2.0 5.7 5.5 5.8
101 Coronary atherosclerosis (coronary artery disease) 810.4 640.7 596.1 33.259 27.976 33.259 2.3 1.7 1.5 6.5 4.9 4.5
106 Cardiac dysrhythmias (irregular heart beat) 402.5 477.5 468.8 10.338 12.693 10.338 1.2 1.2 1.2 3.2 3.7 3.5
203 Osteoarthritis (degenerative joint disease) 299.8 404.9 419.2 10.922 17.461 10.922 0.9 1.0 1.1 2.4 2.9 3.1
Source: AHRQ, Center for Delivery, Organization, and Markets, Healthcare Cost and Utilization Project, Nationwide Inpatient Sample, 1997, 2004 and 2005.
* Includes a small number of discharges (less than 55,000 or 0.1 percent) with missing age.

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